Citrus paradisi antimicrobial activity: an integrative review
DOI:
https://doi.org/10.70151/de42qh79Keywords:
Anti-infectious agents, Dentistry, Citrus paradisiAbstract
Recent search for medicinal and nutritional alternatives has highlighted the search for local plants with beneficial properties in a specific region. Consequently, several surveys have assessed the potential and health benefits of such plants. In the present, we conducted a literature review on the potential medicinal and nutritional use of Citrus paradisi on the databases of PubMed, EMBASE, Biblioteca Virtual em Saúde (BVS), Cochrane Library, and Web of Science using the descriptors selected in MeSH, DeCs, and Entree. The searches were conducted in October 2022. The inclusion criterion applied for the enrolled articles were publication in the last 10 years, excluding literature reviews and case studies. Subsequently, 4 articles were selected for the present literature review. Based on our review, Ci. paradisi has so far presented with promising outcomes against pathogenic bacteria such as Escherichia coli, Pseudomonas aeruginosa, Salmonella spp., Helicobacter pilori, and Enterococcus faecalis. These study results suggested differences in the action of the extracts from this plant on Staphylococcus aureus, although no effect was recorded against the bacteria Typhimurium spp., Listeria monocytogenes, and Staphylococcus epidermitis. Regarding fungi, Candida albicans, Candida glabrata, Aspergillus fumigatus, and Scedosporium apiospermum were found to be sensitive to grapefruit essential oil, while Fusarium avenaceum, F. culmorum, F. graminearum, and F. oxysporum were found to be resistant. Thus, this plant possesses an antimicrobial potential against some microorganisms, albeit further studies are warranted for a more efficient analysis of the action against bacteria and before its potential clinical application.
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