Biological potential of the seed extract and fractions of Artocarpus heterophyllus

Authors

DOI:

https://doi.org/10.70151/vjmebk60

Keywords:

Artocarpus heterophyllus, Plant extract, Antibacterial activity, Antioxidant capacity

Abstract

Artocarpus heterophyllus is a tree of Indian origin that was adapted in Brazil and spread throughout the country. Popularly known as jackfruit, it is an invasive species with sweetened fruits that can reach up to 35 kg and is consumed by various animals. Its pulp is rich in carbohydrates, vitamins, lipids, minerals, and secondary compounds. In addition to pulp consumption, the seeds are cooked or roasted and represent a great source of proteins, vitamins, and carbohydrates. The objective of this study was to evaluate the biological potential of the ethanolic crude extract and the aqueous, chloroform, ethyl acetate, and hexane fractions of A. heterophyllus seeds. Antioxidant and antibacterial activities, secondary compounds and total phenolic were also evaluated. All fractions evaluated showed antibacterial activity. The hexane fraction showed better results in two antioxidant activities tested. The ethanolic extract and hexane fraction showed high content of phenolic compounds. A. heterophyllus seeds have high antioxidant and antibacterial potential, which may be associated with the presence of secondary metabolites, such as phenols, flavones, flavonols, and xanthones.

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Author Biographies

  • Maria Emília Brito da Silva, Universidade Federal Rural de Pernambuco

    Departamento de Morfologia e Fisiologia Animal

  • Edson Flávio Teixeira da Silva, Universidade Federal Rural de Pernambuco

    Departamento de Morfologia e Fisiologia Animal

  • Maria Tamires Alves Espindola, Universidade Federal Rural de Pernambuco

    Departamento de Morfologia e Fisiologia Animal

References

Ajiboye BO, Ojo OA, Adeyonu O, Imiere O, Olayide I, Fadaka A, Oyinloye BA (2016) Inhibitory effect on key enzymes relevant to acute type-2 diabetes and antioxidative activity of ethanolic extract of Artocarpus heterophyllus stem bark. J. Acute Dis. 5:423-429. https://doi.org/10.1016/j.joad.2016.08.011

Azmir J, Zaidul ISM, Rahman MM, Sharif KM, Mohamed A, Sahena F, Jahurul MHA, Ghafoor K, Norulaini NAN, Omar AKM (2013) Techniques for extraction of bioactive compounds from plant materials: A review. J. Food Eng. 117:426-436. https://doi.org/10.1016/j.jfoodeng.2013.01.014

Bhat V, Mutha A, Souza MR (2017) Pharmacognostic and physiochemical studies of Artocarpus heterophyllus seeds. Int. J. Chem. Technol. Res.10:525-536.

Boy HIA, Rutilla AJH, Santos KA, Ty AMT, Yu AI, Mahboob T, Tangpoong J, Nissapatorn V (2018) Recommended medicinal plants as source of natural products: a review. Dig. Chin. Med. 1:131-142. https://doi.org/10.1016/S2589-3777(19)30018-7

Burci LM, Silva CB, Oliveira M, Dalarmi L, Zanin SMW, Miguel OG, Dias JFG, Miguel MD (2015) Determination of antioxidant, radical scavenging activity and total phenolic compounds of Artocarpus heterophyllus (Jackfuit) seeds extracts. J. Med. Plants Res. 9:1013-1020. https://doi.org/10.5897/JMPR2015.5926

Burri SC, Ekholm A, Hakansson Asa, Tonberg E, Rumounen K (2017) Antioxidant capacity and major phenol compounds of horticultural plant materials not usually used. J. Funct. Foods 38:119-127. https://doi.org/10.1016/j.jff.2017.09.003

Caser M, Chitarra W, D’Angiolillo F, Perrone I, Demasi S, Lovisolo C, Pistelli L, Scariot V (2019) Drought stress adaptation modulates plant secondary metabolite production in Salvia dolomitica Codd. Ind. Crops Prod. 129:85-96. https://doi.org/10.1016/j.indcrop.2018.11.068

Cavalcante GM, Neto JFL, Bomfim EO, Flória-Santos MJ (2013) Atividade antimicrobiana de Artocarpus heterophyllus Lam. (Moraceae) sobre o desenvolvimento de Streptococcus pneumoniae e Escherichia coli. Sci. Plena 9:1-7.

Chavez-Santiago JO, Rodríguez-Castillejos GC, Montenegro G, Bridi R, Valdés-Gómez H, Alvarado-Reyna S, Castillo-Ruiz O, Santiago-Adame R (2022) Phenolic content, antioxidant and antifungical activity of jackfruit extracts (Artocarpus heterophyllus Lam.). Food Sci. Technol. 42:e02221. https://doi.org/10.1590/fst.02221

Chowdhury FA, Raman MA, Mian AJ (1997) Distribution of free sugars and fatty acids in jackfruit (Artocarpus heterophyllus). Food Chem. 60:25-28.

Duan XJ, Zhang WW, Li XM, Wang BG (2006) Evaluation of antioxidant property of extract and fractions obtained from a red alga, Polysiphonia urceolata. Food Chem. 95:37-43. https://doi.org/10.1016/j.foodchem.2004.12.015

Fernandez F, Ferreres F, Gil-Izquierdo A, Oliveira AP, Valentão P, Andrade P (2017) Accumulation of primary and secondary metabolites in edible jackfruit seed tissues and scavenging of reactive nitrogen species. Food Chem. 233:85-95. https://doi.org/10.1016/j.foodchem.2017.04.068

Ferreira DF (2011) Sisvar: a computer statistical analysis system. Ciência e Agrotecnologia (UFLA) 35:1039-1042. https://doi.org/10.1590/S1413-70542011000600001

Hernández-Ledesma B, Miralles B, Amigo L, Ramos L, Recio I (2005) Identification of antioxidant and ACE-inhibitory peptides in fermented milk. J. Sci. Food Agric. 85:1041-1048. https://doi.org/10.1002/jsfa.2063

Jagtap UB, Bapat VA (2010) Artocarpus : a review of its traditional uses, phytochemistry and pharmacology. J. Ethnopharm. 129:142-166. https://doi.org/10.1016/j.jep.2010.03.031

Jagtap UB, Bapat VA (2013) Green synthesis of silver nanoparticles using Artocarpus heterophyllus Lam. seed extract and its antibacterial activity. Ind. Crops Prod. 46:132-137. https://doi.org/10.1016/j.indcrop.2013.01.019

Li Y, Jiang B, Zhang T, Mu W, Liu J (2008) Antioxidant and free radical-scavenging activities of chickpea protein hydrolysate (CPH). Food Chem. 106:444-450. https://doi.org/10.1016/j.foodchem.2007.04.067

Matos FJA (1997). Introdução à Fitoquímica Experimental. 2 ed. Fortaleza: Edições UFC. 141.

Nagala S, Yekula M, Tamanam RR (2013) Antioxidant and gas chromatographic analysis of five varieties of jackfruit (Artocarpus) seed oils. Drug Invention Today 5:315-320. https://doi.org/10.1016/j.dit.2013.08.001

Oliveira-Júnior RG, Ferraz CA, Pontes M, Cavalcante NB, Araújoa ECC, Oliveira AP, Picot L, Rolim L, Almeida JGS (2018) Antibacterial activity of terpenoids isolated from Cnidoscolus quercifolius Pohl (Euphorbiaceae), a Brazilian medicinal plant from Caatinga biome. Eur. J. Integr. Med. 24:30-34. https://doi.org/10.1016/j.eujim.2018.10.011

Perdomomo M, Magalhães LM (2013) Ação alelopática da jaqueira (Artocarpus heterophyllus) em laboratório. Braz. J. Forestry Envirom.14:52-55.

Pereira VJ, Kaplan MAC (2013) Artocarpus: Um gênero exótico de grande bioatividade. Floresta e Ambiente 20:1-15. http://dx.doi.org/10.4322/floram.2012.075

Pownall TL, Udenigwe CC, Aluko RE (2010) Amino acid composition and antioxidant properties of pea seed (Pisum sativum L.) Enzymatic protein hydrolysate fractions. J. Agric. Food Chem. 58:4712-4718. https://doi.org/10.1021/jf904456r

Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol. Med. 26:1231-1237. https://doi.org/10.1016/s0891-5849(98)00315-3

Saxena A, Tanushree M, Raju PS, Bawa AS (2015) Optimization of pretreatment and evaluation of quality of jackfruit (Artocarpus heterophyllus) bulb crisps developed using combination drying. Food Bioprod. Process. 95:106-117.

Slinkard K, Singleton VL (1997) Total phenol analysis: automation and comparison with manual methods. Am. J. Enology Viticulture 28:49-55.

Trindade MB, Soares-Costa JLSLA, Montiero-Moreira AC, Moreira RA, Oliva MLV, Beltramini LM (2006) Structural characterization of novel chitin-binding lectins from the genus Artocarpus and their antifungal activity. Biochim. Biophys Acta 1764:146-152. https://doi.org/10.1016/j.bbapap.2005.09.011

Wang XL, Di XX, Shen T, Wang AQ, Wang XN (2017) New phenolic compounds from the leaves of Artocarpus heterophyllus. Chin. Chem. Lett. 28:37-40. https://doi.org/10.1016/j.cclet.2016.06.024

Wu S, Qi W, Li T, Lu D, Su R, He Z (2013) Simultaneous production of multi-functional peptides by pancreatic hydrolysis of bovine casein in an enzymatic membrane reactor via combinational chromatography. Food Chem. 141:2944-2951. https://doi.org/10.1016/j.foodchem.2013.05.050

Yuan WJ, Yuan JB, Peng JB, Ding YQ, Zhu JX, Ren G (2017) Fitoterapia Flavonoids from the roots of Artocarpus heterophyllus. Fitoterapia 117:133-137. https://doi.org/10.1016/j.fitote.2017.01.016

Zhang Y, Duan X, Zhuang Y (2012) Purification and characterization of novel antioxidant peptides from enzymatic hydrolysates of tilapia (Oreochromis niloticus) skin gelatin. Peptides 38:13-21. https://doi.org/10.1016/j.peptides.2012.08.014

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Published

2024-09-17

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How to Cite

Biological potential of the seed extract and fractions of Artocarpus heterophyllus. (2024). Revista Brasileira De Plantas Medicinais, 24(4), 145-152. https://doi.org/10.70151/vjmebk60