Pharmacological Activities of the Phenolic Constituents from Anacardium occidentale L. (Anacardiaceae): A Systematic Review

Authors

DOI:

https://doi.org/10.70151/9yzqbx06

Keywords:

Anacardic acid, Cardol, Cardanol, Phenolic Constituents, Pharmacology, Anacardium occidentale

Abstract

The phenolic compounds present in cashew nut shell liquid (Anacardium occidentale L.– Anacardiaceae) present several pharmacological activities that justify the high number of research studies using these compounds. Among these molecules we can highlight the phenolic constituents such as anacardic acid, cardanol and cardol. The aim of this systematic review was to investigate the pharmacological activities of anacardic acids, cardol and cardanol described in scientific studies published in the literature. The PRISMA methodology was used to perform the bibliographic search applied to the LILACS, PubMed®, Scielo®, SciFinder® and science direct databases, without language or region restrictions, considering articles published between the years 2014 and 2023. The results recovered 52 articles eligible for this review after applying the exclusion and selection criteria. 2 types of pharmacological activities were described, especially: antioxidant, anti-inflammatory, antibacterial, cytotoxic and antiparasitic activity . Most of the studies involved in vitro (20) and in vivo (18) pharmacological evaluation methods. The phenolic compounds of A. occidentale presented a great pharmacological potential to be explored. The use of in silico pharmacology can additionally help in the description of physical-chemical, pharmacokinetic and pharmacodynamic, enabling the exploration of pharmacological potential.

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Author Biographies

  • Vyvian Dias Miranda Soares, State University of Southwest Bahia

    Graduate Program in Chemistry, Department of Science and Technologies

  • Rubens Santos Barreto, State University of Feira de Santana

    Graduate Program in Plant Genetic Resources, Department of Exact Sciences

  • Vilisaimon da Silva de Jesus, State University of Southwest Bahia

    Graduate Program in Chemistry, Department of Science and Technologies

  • Marluce Xavier Santos, State University of Southwest Bahia

    Graduate Program in Chemistry, Department of Science and Technologies

  • Naiane Oliveira Santos, State University of Santa Cruz

    Graduate Program in Genetics and Molecular Biology

  • Bruno Silva Andrade, State University of Southwest Bahia

    Laboratory of Bioinformatics and Computational Chemistry, Department of Biological Sciences

  • Wagner Rodrigues de Assis Soares, State University of Southwest Bahia

    Laboratory of Bioinformatics and Computational Chemistry, Department of Biological Sciences

    Department of Health II

  • Rosane Moura Aguiar, State University of Southwest Bahia

    Graduate Program in Chemistry, Department of Science and Technologies

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2024-09-17

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Vol. 24 No. 4 (2022)

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Pharmacological Activities of the Phenolic Constituents from Anacardium occidentale L. (Anacardiaceae): A Systematic Review. (2024). Revista Brasileira De Plantas Medicinais Brazilian Journal of Medicinal Plants, 24(4), 134-144. https://doi.org/10.70151/9yzqbx06