Study on the Potential of Resveratrol as Chemotherapy for Breast Cancer
DOI:
https://doi.org/10.70151/m6vf0205Keywords:
Breast tumor, Antitumoral agent, PhytotherapyAbstract
Besides the early diagnostic and the breast cancer treatment advances, the mortality and morbidity related to this disease remain high. Resveratrol (3,5,4'-trihydroxystilbene), present in high concentrations in grapes and red wine, has been associated with human health benefits such as anti-tumor, anti-inflammatory, antioxidant, among others. The objective of this work is to review the literature on the potential of Resveratrol as chemotherapy for breast cancer. To carry out this study, sources available in electronic media were used. The reference period was that between 2000 and 2015 and the main key words used were: "resveratrol and breast cancer”. We found several studies showing the antitumor effect of resveratrol in in vivo and in vitro breast cancer models, with effect in several cellular and molecular parameters. Although the review has shown that supplementation of resveratrol can have many benefits in reducing the risk of breast cancer, some studies have shown no effect or a negative effect on these tumors, indicating that greater care should be taken to implement the results obtained from animal models to humans.
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