Evaluation of the toxicity of essential oil from leaves of Ocotea puberula against Artemia salina
DOI:
https://doi.org/10.70151/yv1s0r89Keywords:
Lauraceae, microcrustacean, lethality, medicinal potential, volatile oilsAbstract
Worldwide, the resistance of pathogens has increased as drugs already used in the control of pathogenic microorganisms to humans, expanding to advances in studies with natural products for the protection of bioactive substances for the protection of new agents. Thus, the study had the effect of evaluating the toxicity of the essential oil of the leaves of Ocotea puberula in comparison to the bioassay with Artemia salina. The leaves of O. puberula were collected at the Che Kamba'i Site, in the Municipality of Mundo Novo/MS in March 2014. The essential oil was obtained by hydrodistillation and bioassay before A. salina was performed in different concentrations. The test of A. salina is equal to DL50 equal to 10.3 μg/ml that is, the dose of 50% of the crustaceans, in the dose of 3.9 μg/ml, corresponding to a highly toxic. Results showed potential for a biotechnology of drugs, with great interest for the antitumor application. Other biological studies are needed to support research with O. puberula. Extraction of essential oil from leaves is not one of the most difficult forms of extinction.
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