Community home pharmacies in Maquiné (RS) an ethnopharmacologial avaluation
DOI:
https://doi.org/10.70151/4c28s974Keywords:
Antimicrobial activity, Ethnopharmacology, Rio Grande do Sul, plants medicinal, medicine traditionalAbstract
In the state of Rio Grande do Sul (Brazil), the use of medicinal plants is particularly common in rural areas, where the primary health care is particularly inadequate. A remarkable grass root oriented health movement known as "Farmácias Caseiras Comunitárias" (FCC, "Community home pharmacies") is supported by the Rural Female Workers Movement as much as NGOs associated to the Catholic Church. This study reports an ethnopharmacological appraisal of remedies prepared in Solidão FCC, in the city of Maquiné. The elixir and tinctures for treating conditions likely to be associated to microorganisms were evaluated against seven microorganisms using the diffusion agar test. This screening revealed that these formulations were devoid of in vitro activity, at least against seven common pathogens. As a means of benefit sharing the selected species were thoroughly reviewed in the appropriate scientific literature, in order to attain a therapeutic/toxic categorization.
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References
ADEBAJO, A.C., OLOKI, K.J., ALADESANMI, A.J. Antimicrobial activity of the leaf extract of Eugenia uniflora. Phytotherapy Research, v.36, p.258-9, 1989.
ALI, M.I.A., SHALABY, N.M.M., ELGAMAL, M.H.A. et al. Antifungal effects of different plant extracts and their major components of selected aloe species. Phytotherapy Research, v. 13 п.5, p.401-7, 1999.
ALICE, C.B., VARGAS, V.M.F., SILVA, G.A.A.B., et al. Screening of plants used in South Brazilian folk medicine. Journal of Ethnopharmacology, v.35, n.2, p.165-71, 1991.
ALKOFAHI, A., BATSHOUN, R., OWAIS, W. et al. Biological activity of some jordanian medicinal plant extracts. Fitoterapia, v.67, п.5, р.435-42, 1996.
ALMEIDA, C.E., KARNIKOWSKI, M.G., FOLETO, R. et al. Analysis of antidiarrhoeic effect of plants used in popular medicine. Revista de Saúde Pública, v.29, п.6, p.428-33, 1995.
AMOROZO, M.C.M. A abordagem etnobotanica na pesquisa de plantas medicinais. In: DI STASI, L.C. Plantas medicinais: arte e ciência. um guia de estudo interdisciplinar. São Paulo: Editora da Universidade Estadual Paulista, 1996. p.47-68.
ANAMA Avaliação etnobiológica e ecológica da samambaia-preta (Rumohra adiantiformis (G.Forest.) Ching) no município de Maquiné. Porto Alegre: Secretaria Estadual do Meio Ambiente, 2002. 106p. (Relatório Final),
ANAMA/PGDR-UFRGS Avaliação etnobiológica e socioeconômica da samambaia-preta (Rumohra adiantiformis (G.Forest.) Ching) na região da Encosta Atlântica do Estado. Pesquisa por Demanda - RS RURAL, Porto Alegre: Secretaria de Agricultura e Abastecimento RS, 2003. 111p. (Relatório Final)
BEHNINGER, C., ABEL, G., RODER, E., et al. Studies on the effect of an alkaloid extract of Symphytum officinale on human lymphocyte cultures. Planta Medica, v.55, п.6, p.518-22, 1989.
BHAKUNI, D.S., DHAR, M.L., DHAR, M.M. et al. Screening of Indian plants for biological activity. Part III. Indian Journal of Experimental Biology, v.9, p.91-110, 1971.
BHAUMIK, A., SHARMA, M.C. Therapeutic efficacy of two herbal preparations in induced hepatopathy in sheep. Journal of Research in Indian Medicine, v.12, n.1, p.33-42, 1993.
BIANCHI, N.R., MACHADO, C.A., ALICE, C.B. et al. Estudo da toxicidade da Luehea divaricata Mart & Zucc. Revista Brasileira de Farmácia, v.72, n.3, p.57-8, 1991.
BRESOLIN, S., VARGAS, V.M.F. Mutagenic potencies of medicinal plants screened in the Ames test. Phytotherapy Research, v.7, n.3, p.260-2, 1993.
CÁCERES, A., CANO, O., SAMAYOA, B., et al. Plants used in Guatemala for the treatment of gastrointestinal disorders. 1. Screening of 84 plants against enterobacteria. Journal of Ethnopharmacology, v.30, p.55-73, 1990.
CÁCERES, A., ALVAREZ, A.V., OVANDO, A.E. et al. Plants used in Guatemala for the treatment of respiratory diseases. 1. Screening of 68 plants against gram-positive bacteria. Journal of Ethnopharmacology. v.31, p. 193-208, 1991.
CARTA DE PORTO ALEGRE. Comissão de Saúde e Meio Ambiente da Assembléia Legislativa, p. 173-5, 1998.
COELHO DE SOUZA, G., HAAS, A.P.S., VON POSER, G.L. et al. Ethnopharmacological studies of antimicrobial remedies in Rio Grande do Sul (Brazil). Journal of Ethnopharmacology, 2003, no prelo.
CONY, J. Seminário Plantas Vivas. Produção de Medicamentos Fitoterápicos. Comissão de Saúde e Meio Ambiente. Porto Alegre: Assembléia Legislativa RS, 1998, 175p.
COUET, C.E., CREWS, C., HANLEY, A.B. Analysis, separation, and bioassay of pyrrolizidine alkaloids from comfrey (Symphytum officinale). Natural Toxins, v.4, n.4, p.163-7, 1996.
Comissão de Saúde do Meio Ambiente- CDMA. Plantas Vivas: produção de medicamentos fitoterápicos. Porto Alegre: Assembléia Legislativa RS, 1998. 175p.
DABRAL, P.K., SHARMA, R.K. Evaluation of the role of rumalaya and geriforte in chronic arthritis A preliminary study. Probe, v.22, n.2, p.120-7, 1983.
DUARTE, M.L.P. Bruxinhas de Deus. A serviço da vida. Movimento de Mulheres Trabalhadoras Rurais. Porto Alegre: Editora Evangraf, 2002. 52p.
DUARTE, M.L.P., ROSA, M.T., ALVES, M. et al. Solidão: o início do movimento das Farmácias Caseiras Comunitárias e a sede da Fraternidade Semente de Esperança. In: ENCONTRO DE PESQUISADORES DO VALE DO RIO MAQUINĖ, 1, 2000. Anais... Porto Alegre, 2000, p.63.
DUNGEN, F.M., VERMEULEN, N.P.E., FISCHER, F.C. et al. Removal of pyrrolizidine alkaloids from Symphytum tinctures. Their toxicity towards isolated hepatocytes. Pharmaceutisch Weekblad, v.9, n.4, p.222-31,1987.
EL-SHABRAWY, A.O. Essential oil composition and tannin contents of the leaves of Eugenia uniflora L. grown in Egypt. Bulletin of the Faculty of Pharmacy, v.33, n.3, p.17-21, 1995.
FARNSWORTH, N.R. (ed). NAPRALERT database. Chicago, University of Illinois at Chicago, IL, March 15, 1995 production (an on-line database available directly through the University of Illinois at Chicago or through the Scientific and Technical Network (STN) of Chemical Abstracts Services). Chicago. University of Illinois, 2003.
FERREIRA, L.O., COELHO DE SOUZA, G.P., MAGALHÃES, R.G. et al. As Bruxinhas de Deus: Farmácias Caseiras Comunitárias em Maquine, RS. In: SIMPOSIO BRASILEIRO DE ETNOBIOLOGIA, 2, 1998, São Carlos. Anais... São Carlos, 1998. 69p.
FUJITA, K., YAMADA, Y., AZUMA, K.S. et al. Effect of leaf extracts of Aloe arborescens subsp. natalensis Berger on growth of Trichophyton mentagrophytes. Antimicrobial Agents and Chemotherapy, v.14, p.132-6, 1978.
FURMANOWA, M., GUZEWSKA, J., BELDOWSKA, B. Mutagenic effects of aqueous extracts of Symphytum officinale L.. And of its alkaloidal fractions. Journal of Applied Toxicology, v.3, n.3, p. 127-30, 1983.
GARLET, T.M.B. Levantamento das plantas medicinais utilizadas no município de Cruz Alta, RS, Brasil. 2000. 211p. Dossertação (Mestrado)- Universidade Federal do Rio Grande do Sul, Porto Alegre.
HAN, B.H., CHI, H.J., HAN,Y.N. et al. Screening on the anti-inflammatory activity of crude drugs. Korean Journal of Pharmacognosy, v.4, п.3, p.205-9, 1972.
HEINRICH, M., KUHNT, M., WRIGHT, C.W. et al. Parasitological and microbiological evaluation of mixe indian medicinal plants (Mexico). Journal of Ethnopharmacology, v.36, n. 1, p.81-5, 1992.
HONG, H.S., LEE, K.H., KIM, J.H. et al. The comparative of inhibitory effect of various solvent extracts from Aloe arborescens and Aloe vera on tumor cell lines using clonogenic assay. Korean Journal of Pharmacognosy, v.30, n.3, p.275-9, 1999.
INAHATA, K., NAKASURI, T. Mutagen inhibitors containing Aloe extracts. Patent-japan Kokai Tokkyo Koho-07, v.53, n.397, p. 13, 1995.
IOSIFOV, I. Experiment using cell cultures to determine toxicity of drugs of plant origin. Problemi na Vutreshnata Meditsina, v.9, p. 155-61, 1981.
IZZO, A.A., DI CARLO, G., BISCARDI, D. et al. Biological screening of Italian medicinal plants for antibacterial activity. Phytotherapy Research, v.9, n.4, p.281-6, 1995.
JAYARAM, S., THYAGARAJAN, S.P., PANCHANADAM, M., et al. Anti-hepatitis-b virus properties of Phyllanthus niruri Linn. and Eclipta alba Hassk: in vitro and in vivo safety studies. Bio-Medicine, v.7, n.2, p.9-16, 1987.
KAMEYAMA, S., SHINHO, M. Wound-healing compositions from Aloe arborescens extracts. Patent-japan Kokai Tokkyo Koho-79, v.151, n.113, р.5 -12,1070.
KAWAI, K., BEPPU, H., SHIMPO, K. et al. In vivo effects of Aloe arborescens Miller var. natalensis Berger (kidachi aloe) on experimental tinea pedis in guinea-pig feet. Phytotherapy Research, v.12, n.3, p.178-82, 1998.
KITISIN, T. Pharmacological Studies. 3. Phyllanthus niruri. Sirriaj Hospital Gazette, v. 4, p.641-9, 1952.
KUBO, R.R. Levantamento das plantas de uso medicinal em Coronel Bicaco, RS. 1997. 163p. Dissertação (Mestrado)- Universidade Federal do Rio Grande do Sul, Porto Alegre.
LI, F.K. Problems concerning artificial abortion through oral administration of traditional drugs. Ha-Erh-Pin Chung-l, v. 1, p.11-4, 1965.
MARODIN, S.M. Plantas utilizadas como medicinais no município de Dom Pedro de Alcântara, Rio Grande do Sul. 2000. 413p. Dissertação (Mestrado) Universidade Federal do Rio Grande do Sul, Porto Alegre.
MASCOLO, N., AUTORE, G., CAPASSO, F. et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytotherapy Research, v. 1, n. 1. p.28-31, 1987.
MAY, G., WILLUHN, G. Antiviral activity of aqueous extracts from medicinal plants in tissue cultures. Arzneimittel Forschung, v.28, n. 1, p. 1-7, 1978.
MEIXIA, W., HAOWEI, C., YANJUN, L. et al. Observations of the efficacy of Phyllanthus spp. in treating patients with chronic hepatitis B. Chung-Kuo Chung Yao Tsa Chih, v. 19, n. 12, p.750-2, 1994.
MESIA, L.T.K., NGIMBI, N.P., CHRIMWAMI, B. et al. A.L. In vitro antimalarial activity of Cassia occidentalis, Morinda morindoides and Phyllanthus niruri. Annals of Tropical Medicine and Parasitology, v.95, n. 1, p.47-57, 2001.
NAKANISHI, G., AKAHORI, M., OHMI, T.et al. Feed efficiency of comfrey for pigs. Nihon Daigaku Nojuigakubu Gakujutsu Kenkyu Hokoku, v.35, p.271-81, 1978.
NAKASUGI, T., KOMAI, K. Antimutagen of aloe plants. Kinki Daigaku Nogakubu Kiyo, v.27, p.47-54, 1994.
NAM, S.H., YANG, M.S. Isolation of cytotoxic substances from Chrysanthemum boreale M. Han'guk Nonghwa Hakhoe Chi, v.38, n.3, p.273-7, 1995.
OKADA, K. Studies on in vitro and in vivo effects of Aloe extract on hepatocarcinogenesis. Wakayama Igaku, v.48, n. 1, p.85-95, 1997.
PARK, J.G., HYUN, J.W., LIM, K.H. et al. Antineoplastic effect of extracts from traditional medicinal plants. Korean Journal of Pharmacognosy, v.24, n.3, p.223-30, 1993.
PETROVICK, P.R., GONZALEZ ORTEGA, G. BASSANI. V.L. From a medicinal plant to a pharmaceutical dosage form. A (still) long way for the brazilian medicinal plants. Ciência e Cultura, v.49, n.5/6, p.364-9. 1997.
POSSAMAI, R.M. Levantamento etnobotânico das plantas de uso medicinal em Mariana Pimentel, RS. 2000. 108 p. Dissertação (Mestrado)- Universidade Federal do Rio Grande do Sul. Porto Alegre.
RAO, Y.S. Experimental production of liver damage and its protection with Phyllanthus niruri and Capparis spinosa (both ingredients of liv.52) in white albino rats. Probe, v.24, n.2, p.117-9, 1985.
RIOS, J.L., RECIO, M.C., VILLAR, A. Screening methods for natural products with antimicrobial activity: a review of the literature. Journal of Ethnopharmacology, v.23, p.127-49, 1988.
RUNNEBAUM, B., RABE, T., KIESEL, L. et al. Biological evaluation of some medicinal plant extracts for contraceptive efficacy in females. Future aspects in contraception. Female contraception, Boston: MTP Press, 1984. . 115-28.
SANTOS, A.R.S., DE CAMPOS, R.A.P., MIGUEL, O.G. et al. Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae). Journal of Ethnopharmacology, v.72, n 1.1/2 p.229-38, 2000.
SANTOS, A.R.S., FILHO, V.C., YUNES, R.A. et al. Analysis of the mechanisms underlying antinociceptive effect of the extracts of plants from the genus Phyllanthus. General Pharmacology, v.26, n. 7, p. 1499-506, 1995.
SANTOS, A.R.S., FILHO, V.C., YUNES, R.A. et al. Further studies on the antinociceptive action of the hydroalcohlic extracts from plants on the genus Phyllanthus. Journal of Pharmacy and Pharmacology, v.47, n.1, p.66-71, 1995a.
SCHMEDA-HIRSCHMANN, G., THEODULOZ, C., FRANCO, L. et al. Preliminary pharmacological studies on Eugenia uniflora leaves: xanthine oxidase inhibitory activity. Journal of Ethnopharmacology, v.21, п.2, p. 183-6, 1987.
SHIMPO, K., CHIHARA, T., BEPPU, H. et al. Inhibition of azoxymethane-induced aberrant crypt foci formation in rat colorectum by whole leaf Aloe arborescens Miller var. natalensis Berger. Phytotherapy Research, v.15, n.8, p.705-11, 2001.
SIMÕES, C.M.O., FALKENBERG, M., AULER MENTZ, L. et al. Antiviral activity of South Brazilian medicinal plant extracts. Phytomedicine, v.6, n.3, p.205-14, 1999,
SIMÕES, C.M.Ο., MENTZ, L.A., SCHENKEL, E.P. et al. Plantas da medicina popular no Rio Grande do Sul. 4. ed., Porto Alegre: Editora da Universidade Federal do Rio Grande do Sul, 1995. 173p.
SONAGLIO, D., GONZALEZ ORTEGA, G., PETROVICK, P.R. et al. Desenvolvimento tecnológico de produção de fitoterápicos. In: SIMÕES. C.M.O, SCHENKEL. E.P, GOSMANNING, G. et al. Farmacognosia: da planta ao medicamento. Porto Alegre e Florianópolis: Editora da UFSC e da UFRGS, 1999. p.221-58.
SUGA, T., HIRATA, T. The efficacy of the Aloe plants chemical constituents and biological activities. Cosmet Toiletries, v.98, n.6, p. 105-8, 1983.
TARLE, D., PETRICIC, J., KUPINIC, M. Antimicrobial activity of common comfrey (Symphytum officinale L.). Acta Pharmaceutica Jugoslavia, v.32, p.235-7, 1982.
THABREW, M.R., HUGHES, R.D. Phytogenic agents in the therapy of liver disease. Phytotherapy Research, v.10, n.6, p.461-7, 1996.
UENO, H., HORIE, S., NISHI, Y.N. et al. Chemical and pharmaceutical studies on medicinal plants in Paraguay. Geraniin, an angiotensin-converting enzyme inhibitor from "Paraparai Mi", Phyllanthus niruri. Journal of Natural Products, v.51, n.2, p.357-9, 1988.
UMARANI, D., DEVAKI, T., GOVINDARAJU, P. et al. Ethanol induced metabolic alterations and the effect of Phyllanthus niruri in their reversal. Ancient Science of Life, v.4, n.3, p. 174-80, 1985.
VARGAS, V.M.F., MOTTA, V.E.P., ALICE, C.B. et al. Estudo da atividade mutagenica de extratos vegetais com uso em medicina popular. Revista Brasileira de Farmácia, v.70, n.3, p.65-7, 1989.
VARGAS, V.M.F., GUIDOBONO, R.R., HENRIQUES, J. A. P. Genotoxicity of plant extracts. Memórias do Instituto Oswaldo Cruz, v.86, p.67-70, 1991.
VIANA, A.M., MORENO, F.N., CAMPOS, M.M. et al. Analgesic effects of callus culture extracts from selected species of Phyllanthus in mice. Journal of Pharmacy and Pharmacology, v.46, n.9, p.755-9, 1994.
WEBER, A. A mnemonic three-letter acronyms for the families of vascular plants: a device for more effective herbarium curation, Taxon, v.3, n.1, p.74-88, 1982.
WENIGER, B., ROBINAEU, L. Elementos para una farmacopea Caribeña. Seminario Tramil 3, La Habana, Cuba: Ministerio de Salud Publica, 1988, 318p.
WOO, W.S., LEE, E.B., HAN, B.H. Biological evaluation of korean medicinal plants. III. Archives of Pharmacology Research, v.2, p. 127-31, 1979.
YAMAMOTO, M., SUGIYAMA, K., YOKOTA, M. et al. Study of possible pharmacological actions of Aloe arborescens Miller on mouse, hamster and human skin. Japanese Journal of Toxicology and Environmental Health, v.39, n.5, р.409-14, 1993.
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