Yam (Dioscorea sp.): functional food?

Authors

DOI:

https://doi.org/10.70151/ana80188

Keywords:

Yam, Functional food, Health

Abstract

Yam is a tuber with important characteristics. It has been used, among other purposes, such as nutritional additive to add functional properties to preparations. Its use for medicinal purposes has been reported since the 50s by ancient China. Recent studies point to the beneficial effect and reinforce a variety of properties related to the tuber consumption, or its bioactive compounds isolated, such as immunomodulatory, antioxidant and antiinflammatory activity and exert modulatory role in absorption and metabolism of lipids and glucose and be used in the treatment of menopause and prevention of cancer and hypertension. However, the proportional relationship between consumption and benefits as well as the best way to intake, are not clearly established in the literature. Scientific designs which intend to establish this relationship and verify the benefits of yam consumption are required.

Downloads

Download data is not yet available.

Author Biographies

  • Cinthia Karla Rodrigues do Monte-Guedes, Universidade Federal da Paraíba

    Departamento de Nutrição

  • Andrei Felipe Loureiro do Monte Guedes, Universidade Federal Rural de Pernambuco

    Rede Nordeste de Biotecnologia

  • Thayza Cristina Montenegro Stamford, Universidade Federal de Pernambuco

    Departamento de Medicina Tropical

  • Tânia Lúcia Montenegro Stamford, Universidade Federal de Pernambuco

    Departamento de Nutrição

References

Alcantara EH, Shin M-Y, Sohn H-Y, Park Y-M, Kim T, Lim J-H, Jeong H-J, Kwon S-T, Kwun I-S (2011) Diosgenin stimulates osteogenic activity by increasing bone matrix protein synthesis and bone-specific transcription factor Runx2 in osteoblastic MC3T3-E1 cells. J Nutr Biochem 22:1055–1063. https://doi.org/10.1016/j.jnutbio.2010.09.003

Asiedu R, Sartie A (2010) Crops that feed the world 1. yams. Food Secur 2:305–315. https://doi.org/10.1007/s12571-010-0085-0

Brasil. ANVISA – Agência Nacional de Vigilância Sanitária (2016) Available at: http://portal.anvisa.gov.br/. Accessed on: 01 dez 2016.

Brasil. MAPA - Ministério da Agricultura, Pecuária e Abastecimento. Secretaria de Desenvolvimento Agropecuário e Cooperativismo (2010) Manual de Hortaliças Não-Convencionais. Available at: http://www.agricultura.gov.br/arq_editor/file/vegetal/Qualidade/Qualidade%20dos%20Alimentos/Cartilha%20Hortali%C3%A7as_nao-convencionais.pdf. Accessed on: 05 ago 2014.

Brito TT de, Soares LS, Furtado MC, Castro AA, Carnelossi MAG (2011) Composição centesimal de inhame (Dioscorea sp.) in natura e minimamente processado. Sci Ple 7:1–7. Available at: https://www.scientiaplena.org.br/sp/article/view/183. Accessed on: 09 ago 2015.

Chan Y-C, Chang S-C, Liu S-Y, Yang H-L, Hseu Y-C, Liao J-W (2010) Beneficial effects of yam on carbon tetrachloride-induced hepatic fibrosis in rats. J Sci Food Agric 90:161–167. Available at: https://doi.org/10.1002/jsfa.3801

Chen H-L, Wang C-H, Chang C-T, Wang T-C (2003) Effects of taiwanese yam (Dioscorea japonica Thunb var. pseudojaponica Yamamoto) on upper gut function and lipid metabolism in Balb/c mice. Nutrition 19:646–651. https://doi.org/10.1016/S0899-9007(03)00058-3

Chen M, Yang T, Yeh L, Chung H, Wen Y, Lee W, Cheng J (2012) Activation of imidazoline I-2B receptors by allantoin to increase glucose uptake into C2C12 cells. Horm Metab Res 44:268–272. https://doi.org/10.1055/s-0032-1301898

Cheng W-Y, Kuo Y-H, Huang C-J (2007) Isolation and identification of novel estrogenic compounds in yam tuber (Dioscorea alata cv. Tainung No. 2). J Agric Food Chem 55:7350–7358. https://doi.org/10.1021/jf0711690

Chiu C-S, Deng J-S, Chang H-Y, Chen Y-C, Lee M-M, Hou W-C, Lee C-Y, Huang S-S, Huang G-J (2013) Antioxidant and anti-inflammatory properties of taiwanese yam (Dioscorea japonica Thunb. var. pseudojaponica (Hayata) Yamam.) and its reference compounds. Food Chem 141:1087–1096. https://doi.org/10.1016/j.foodchem.2013.04.031

Chiu C-S, Deng J-S, Hsieh M-T, Fan M-J, Lee M-M, Chueh F-S, Han C-K, Lin Y-C, Peng W-H (2009) Yam (Dioscorea pseudojaponica Yamamoto) ameliorates cognition deficit and attenuates oxidative damage in senescent mice induced by D-galactose. Am J Chin Med 37:889–902. https://doi.org/10.1142/S0192415X09007296

Depypere HT, Comhaire FH (2014) Herbal preparations for the menopause: Beyond isoflavones and black cohosh. Maturitas 77:191–194. https://doi.org/10.1016/j.maturitas.2013.11.001

FAO - Food and Agriculture Organization (2013) Dioscorea cayennensis. Available at: http://ecocrop.fao.org/ecocrop/srv/en/cropView?id=5369. Accessed on: 10 nov 2014.

Foster-Powell K, Holt SH, Brand-Miller JC (2002) International table of glycemic index and glycemic load values: 2002. Am J Clin Nutr 76:5–56. https://doi.org/10.1093/ajcn/76.1.5

Fu LS, Ko YH, Lin KW, Hsu JY, Chu JJ, Chi CS (2009) Dioscorin protects tight junction protein expression in A549 human airway epithelium cells from dust mite damage. J Microbiol Immunol Infect 42:457–63

Gil H-W, Lee E-Y, Lee J-H, Kim Y-S, Lee B-E, Suk J-W, Song H-Y (2015) Dioscorea batatas extract attenuates high-fat diet-induced obesity in mice by decreasing expression of inflammatory cytokines. Med Sci Monit 21:489–95. https://doi.org/10.12659/MSM.891306

Guedes CKRM (2014) Potencial tecnológico do inhame (Dioscorea cayennensis) na formulação de bebidas funcionais à base de frutas tropicais e Lactobacillus casei. 190p. Doutorado em nutrição, Departamento de Nutrição, Universidade Federal de Pernambuco, Recife, Brasil.

Han C-H, Liu J-C, Fang S-U, Hou W-C (2013) Antioxidant activities of the synthesized thiol-contained peptides derived from computer-aided pepsin hydrolysis of yam tuber storage protein, dioscorin. Food Chem 138:923–930. https://doi.org/10.1016/j.foodchem.2012.11.101

Hashimoto N, Noda T, Kim S-J, Sarker M, Yamauchi H, Takigawa S, Matsuura-Endo C, Suzuki T, Han K-H, Fukushima M (2009) Yam contributes to improvement of glucose metabolism in rats. Plant Foods Hum Nutr 64:193–198. https://doi.org/10.1007/s11130-009-0126-z

Hou W-C, Hsu F-L, Lee M-H (2002) Yam (Dioscorea batatas) tuber mucilage exhibited antioxidant activities in vitro. Planta Med 68:1072–1076. https://doi.org/10.1055/s-2002-36356

Hou W-C, Lee M-H, Chen H-J, Liang W-L, Han C-H, Liu Y-W, Lin Y-H (2001) Antioxidant activities of dioscorin, the storage pein of yam (Dioscorea batatas Decne) tuber. J Agric Food Chem 49:4956–4960. https://doi.org/10.1021/jf010606m

Hsu F-L, Lin Y-H, Lee M-H, Lin C-L, Hou W-C (2002) Both dioscorin, the tuber storage protein of yam (Dioscorea alata cv. Tainong No. 1), and its peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activities. J Agric Food Chem 50:6109–13

Hsu J-Y, Chu J-J, Chou M-C, Chen Y-W (2013a) Dioscorin pre-treatment protects A549 human airway epithelial cells from hydrogen peroxide-induced oxidative stress. inflammation 36:1013–1019. https://doi.org/10.1007/s10753-013-9633-z

Hsu K-H, Chang C-C, Tsai H-D, Tsai F-J, Hsieh Y-Y (2008) Effects of yam and diosgenin on calpain systems in skeletal muscle of ovariectomized rats. Taiwan J Obstet Gynecol 47:180–186. https://doi.org/10.1016/S1028-4559(08)60077-7

Hsu Y-J, Weng C-F, Lin K-W, Lin K-C (2013b) Suppression of allergic reactions in ovalbumin-sensitized mice by yam storage proteins dioscorins. J Agric Food Chem 61:11460–11467. https://doi.org/10.1021/jf403480s

Huang C-H, Cheng J-Y, Deng M-C, Chou C-H, Jan T-R (2012) Prebiotic effect of diosgenin, an immunoactive steroidal sapogenin of the Chinese yam. Food Chem 132:428–432. https://doi.org/10.1016/j.foodchem.2011.11.016

Hue SM (2008) Delícias do descobrimento: a gastronomia brasileira no século XVI. 1. ed. Rio de Janeiro: Jorge Zahar. 208p.

Japan - MHLW - Ministry of Health, Labour and Welfare – Japan (2016) Food for Specified Health Uses (FOSHU). Available at: http://www.mhlw.go.jp/english/topics/foodsafety/fhc/02.html. Accessed on: 01 dez. 2016.

Jayachandran KS, Vasanthi HR, Rajamanickama GV (2010) Flavonoid rich fraction of Dioscorea bulbifera Linn. (yam) enhances mitochondrial enzymes and antioxidant status and thereby protects heart from isoproterenol induced myocardial infarction. Curr Pharm Biotechnol 11:887–94. https://doi.org/10.2174/138920110793262033.

Jeon JR, Lee JS, Lee CH, Kim JY, Kim SD, Nam DH (2006) Effect of ethanol extract of dried Chinese yam (Dioscorea batatas) flour containing dioscin on gastrointestinal function in rat model. Arch Pharm Res 29:348–353. https://doi.org/10.1007/BF02968583

Jheng Y-J, Tsai W-Y, Chen K-H, Lin K-W, Chyan C-L, Yang C-C, Lin K-C (2012) Recombinant dioscorins of the yam storage protein expressed in Escherichia coli exhibit antioxidant and immunomodulatory activities. Protein Expr Purif 85:77–85. https://doi.org/10.1016/j.pep.2012.07.001

Laudan R (1996) The Food of Paradise: Exploring Hawaii's Culinary Heritage. 1. ed. Hawai: University of Hawaii Press. 296p.

Lee S-C, Tsai C-C, Chen J-C, Lin C-C, Hu M, Lu S (2002a) The evaluation of reno- and hepato-protective effects of Huai-Shan-Yao (rhizome dioscoreae). Am J Chin Med 30:609–616. https://doi.org/10.1142/S0192415X02000624

Lee S-C, Tsai C-C, Chen J-C, Lin C-C, Hu M, Lu S (2002b) Effects of “chinese yam” on hepato-nephrotoxicity of acetaminophen in rats. Acta Pharmacol Sin 23:503–8

Li SC (1956) Pen-T’sao Kang Mu. Nanjing, China.

Lin P-L, Lin K-W, Weng C-F, Lin K-C (2009) Yam storage protein dioscorins from Dioscorea alata and Dioscorea japonica exhibit distinct immunomodulatory activities in mice. J Agric Food Chem 57:4606–4613. https://doi.org/10.1021/jf8038499

Liu C, Wang Y, Wu C, Pei R, Song J, Chen S, Chen X (2013) Dioscin’s antiviral effect in vitro. Virus Res 172:9–14. https://doi.org/10.1016/j.virusres.2012.12.001

Liu S-F, Chang S-Y, Lee T-C, Chuang L-Y, Guh J-Y, Hung C-Y, Hung T-J, Hung Y-J, Chen P-Y, Hsieh P-F, Yang Y-L (2012) Dioscorea alata attenuates renal interstitial cellular fibrosis by regulating smad- and epithelial-mesenchymal transition signaling pathways. PLoS One 7:e47482. https://doi.org/10.1371/journal.pone.0047482

Liu Y-H, Lin Y-S, Liu D-Z, Han C-H, Chen C-T, Fan M, Hou W-C (2009a) Effects of different types of yam (Dioscorea alata) products on the blood pressure of spontaneously hypertensive rats. Biosci Biotechnol Biochem 73:1371–1376. https://doi.org/10.1271/bbb.90022

Liu Y-W, Liu J-C, Huang C-Y, Wang C-K, Shang H-F, Hou W-C (2009b) Effects of oral administration of yam tuber storage protein, dioscorin, to BALB/c mice for 21-days on immune responses. J Agric Food Chem 57:9274–9279. https://doi.org/10.1021/jf902245k

Liu Y-W, Shang H-F, Wang C-K, Hsu F-L, Hou W-C (2007) Immunomodulatory activity of dioscorin, the storage protein of yam (Dioscorea alata cv. Tainong No. 1) tuber. Food Chem Toxicol 45:2312–2318. https://doi.org/10.1016/j.fct.2007.06.009

Mazzio E, Badisa R, Mack N, Deiab S, Soliman KFA (2014) High throughput screening of natural products for anti-mitotic effects in MDA-MB-231 human breast carcinoma cells. Phyther Res 28:856–867. https://doi.org/10.1002/ptr.5065

Mazzio EA, Soliman KFA (2009) In vitro screening for the tumoricidal properties of international medicinal herbs. Phyther Res 23:385–398. https://doi.org/10.1002/ptr.2636

McAnuff MA, Harding WW, Omoruyi FO, Jacobs H, Morrison EY, Asemota HN (2005) Hypoglycemic effects of steroidal sapogenins isolated from jamaican bitter yam, Dioscorea polygonoides. Food Chem Toxicol 43:1667–1672. https://doi.org/10.1016/j.fct.2005.05.008

Mestres C, Dorthe S, Akisso N, Hounhouigan JD (2004) Prediction of sensorial properties (color and taste) of amala, a paste from yam chips flour of West Africa, through flour biochemical properties. Plant Foods Hum Nutr 59:93–99. https://doi.org/10.1007/s11130-004-0028-z

Miyoshi N, Nagasawa T, Mabuchi R, Yasui Y, Wakabayashi K, Tanaka T, Ohshima H (2011) Chemoprevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by freeze-dried yam sanyaku and Its constituent diosgenin. Cancer Prev Res 4:924–934. https://doi.org/10.1158/1940-6207.CAPR-10-0279

Nagai T, Nagashima T (2006) Functional properties of dioscorin, a soluble viscous protein from japanese yam (Dioscorea opposita Thunb.) tuber mucilage tororo. Z Naturforsch C 61:792–798. https://doi.org/10.1515/znc-2006-11-1204

Nishimura N, Tanabe H, Yamamoto T, Fukushima M (2011) Raw chinese yam (Dioscorea opposita) promotes cecal fermentation and reduces plasma non-HDL cholesterol concentration in rats. J Nutr Sci Vitaminol (Tokyo) 57:340–347. https://doi.org/10.3177/jnsv.57.340

Niu C-S, Chen W, Wu H-T, Cheng K-C, Wen Y-J, Lin K-C, Cheng J-T (2010) Decrease of plasma glucose by allantoin, an active principle of yam (Dioscorea spp.), in streptozotocin-induced diabetic rats. J Agric Food Chem 58:12031–12035. https://doi.org/10.1021/jf103234d

Omoruyi FO (2008) Jamaican bitter yam sapogenin: potential mechanisms of action in diabetes. Plant Foods Hum Nutr 63:135–140. https://doi.org/10.1007/s11130-008-0082-z

Pan C-H, Tsai C-H, Liu F-C, Fan M-J, Sheu M-J, Hsieh W-T, Wu C-H (2013) Influence of different particle processing on hypocholesterolemic and antiatherogenic activities of yam (Dioscorea pseudojaponica ) in cholesterol-fed rabbit model. J Sci Food Agric 93:1278–1283. https://doi.org/10.1002/jsfa.5882

Park M-K, Kwon H-Y, Ahn W-S, Bae S, Rhyu M-R, Lee Y (2009) Estrogen activities and the cellular effects of natural progesterone from wild yam extract in MCF-7 human breast cancer cells. Am J Chin Med 37:159–167. https://doi.org/10.1142/S0192415X09006746

Paula CD de, Pirozi M, Puiatti M, Borges JT, Durango AM (2012) Caracteristicas físicoquímicas e morfológicas de rizóforos de inhame (Dioscorea alata). Biotecnol Sect Agropecu y Agroindustrial 10:61–70

Son IS, Kim JH, Sohn HY, Son KH, Kim JS, Kwon CS (2007) Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats. Biosci Biotechnol Biochem 71:3063–3071. https://doi.org/10.1271/bbb.70472

Tunger L (1975) J. W. Purseglove: Tropical Crops. Monocotyledons. v1&2, 1. ed,Leinen, 607p.Tropical Crops, Dicotyledons, 3. ed, Longman. 1974, 702p. Food / Nahrung 19:519–519. https://doi.org/10.1002/food.19750190533

UNICAMP (2011) Tabela Brasileira de Composição de Alimentos, 4th edn. NEPA-UNICAMP, Campinas

USDA (2013) Germplasm Resources Information Network - (GRIN) [Online Database]. National Germplasm Resources Laboratory, Beltsville, Maryland. Available at: http://www.ars-grin.gov/cgi-bin/npgs/html/taxon.pl?14189. Accessed on: 03 jul. 2014.

Vasanthi HR, Mukherjee S, Ray D, Jayachandran KSP, Lekli I, Das DK (2010) Protective role of air potato (Dioscorea bulbifera) of yam family in myocardial ischemic reperfusion injury. Food Funct 1:278–283. https://doi.org/10.1039/C0FO00048E

Wanasundera JPD, Ravindran G (1994) Nutritional assessment of yam (Dioscorea alata) tubers. Plant Foods Hum Nutr 46:33–39. https://doi.org/10.1007/BF01088459

Wojcikowski K, Wohlmuth H, Johnson DW, Gobe G (2008) Dioscorea villosa (wild yam) induces chronic kidney injury via pro-fibrotic pathways. Food Chem Toxicol 46:3122–3131. https://doi.org/10.1016/j.fct.2008.06.090

Wu W-H, Liu L-Y, Chung C-J, Jou H-J, Wang T-A (2005) Estrogenic effect of yam ingestion in healthy postmenopausal women. J Am Coll Nutr 24:235–243. https://doi.org/10.1080/07315724.2005.10719470

Xiao J, Wang N, Sun B, Cai G (2010) Estrogen receptor mediates the effects of pseudoprotodiocsin on adipogenesis in 3T3-L1 cells. Am J Physiol Physiol 299:C128–C138. https://doi.org/10.1152/ajpcell.00538.2009

Yang MH, Chin Y-W, Yoon KD, Kim J (2014) Phenolic compounds with pancreatic lipase inhibitory activity from Korean yam (Dioscorea opposita). J Enzyme Inhib Med Chem 29:1–6. https://doi.org/10.3109/14756366.2012.742517

Zhao Y, Song H, Fei J, Liang Y, Zhang B, Liu Q, Wang J, Hu P (2012) The effects of chinese yam-epimedium mixture on respiratory function and quality of life in patients with chronic obstructive pulmonary disease. J Tradit Chinese Med 32:203–207. https://doi.org/10.1016/S0254-6272(13)60012-6

Published

2024-09-18

Issue

Section

Articles

How to Cite

Yam (Dioscorea sp.): functional food?. (2024). Revista Brasileira De Plantas Medicinais Brazilian Journal of Medicinal Plants, 21(4), 290-299. https://doi.org/10.70151/ana80188