Anti-adiposity effect of cipó-cravo (Tynanthus fasciculatus), a vine from the Brazilian Atlantic Forest

Authors

DOI:

https://doi.org/10.70151/vkvqrt21

Keywords:

herbal medicines, phytotherapy, adipose tissue, weight loss

Abstract

Tynanthus fasciculatus (Vell.) Miers (Bignoniaceae) is a plant used in traditional medicine in southeastern Brazil, with aphrodisiac, antiparasitic, and tonic effects. Its extracts have a range of categories of active compounds identified, but their effects are scarcely reported in the scientific literature. We described, for the first time, the effects of T. fasciculatus infusion on body weight and adipose tissue depot weight in a Swiss mouse model. All studied doses (100, 200, and 300 mg/kg) caused a significant reduction in the weight of the interscapular brown adipose tissue and the epididymal white adipose tissue depots. The doses of 100 and 200 mg were also effective in controlling body weight gain. The infusion of T. fasciculatus was efficient in reducing adiposity and controlling weight gain.

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Author Biographies

  • Luiz Carlos Maia Ladeira, Universidade Federal de Viçosa

    Departamento de Biologia Geral

  • Eduardo Medeiros Damasceno, Universidade Federal de Viçosa

    Departamento de Biologia Geral

  • Aline Leão de Andrade Bandeira de Melo, Universidade Federal de Viçosa

    Departamento de Biologia Geral

  • Janaina da Silva, Universidade Federal de Viçosa

    Departamento de Biologia Geral

  • Izabel Regina dos Santos Costa Maldonado, Universidade Federal de Viçosa

    Departamento de Biologia Geral

  • Sérgio Luis Pinto da Matta, Universidade Federal de Viçosa

    Departamento de Biologia Geral

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Published

2025-07-21

Issue

Vol. 27 No. 2025 (2025)

Section

Articles

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Copyright (c) 2025 Revista Brasileira de Plantas Medicinais

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How to Cite

Anti-adiposity effect of cipó-cravo (Tynanthus fasciculatus), a vine from the Brazilian Atlantic Forest. (2025). Revista Brasileira De Plantas Medicinais, 27(2025), e2025001. https://doi.org/10.70151/vkvqrt21