Consensus of the medicinal use of Copaifera langsdorffii Desf. in different phytophysiognomies

Authors

DOI:

https://doi.org/10.70151/2hz8n979

Keywords:

Copaíba, Informant consensus, Therapeutic Uses, Different biomes, Ethnobotany

Abstract

The present study had as its objective to carry out an ethnobotanical survey of Copaíba in Cerradão, Carrasco, Wetland and Caatinga phytophysiognomies in the Chapada do Araripe, Northeast, Brazil, with a standardized form. Semi-structured interviews and the snowball technique were used. Usage diversity, plant part consensus and level of fidelity were analyzed to verify the consensus of the usage categories, plant part and indicated diseases. In the study, 61 therapeutic indications were cited for Cerradão (38), Caatinga (33), Pantanal (20) and Carrasco (15), with wound healing, rheumatic arthritis, bone pain, back problems and throat inflammation being the most cited.Despite Cerradão and Caatinga registering a greater number of therapeutic indications, their general level of fidelity was low, ranging from 3.57 to 25 and 4.35 to 26.09, respectively. Of the 13 registered categories, musculoskeletal and skin disorders were the categories with the highest usage diversity values among the studied phytophysiognomies. The data obtained for C. langsdorffii emphasize its therapeutic potential and the need for studies that evaluate the species as a source of biologically active natural products, thus serving as a basis for future studies.

Downloads

Download data is not yet available.

Author Biographies

  • Maria de Oliveira Santos, Regional University of Cariri

    Plant Ecology Laboratory, Department of Biology

  • Bianca Vilar de Almeida, Regional University of Cariri

    Plant Ecology Laboratory, Department of Biology

  • Flávia Geane Torres de Mendonça, Regional University of Cariri

    Plant Ecology Laboratory, Department of Biology

  • Márcia Jordana Ferreira Macêdo, Regional University of Cariri

    Plant Ecology Laboratory, Department of Biology

  • Daiany Alves Ribeiro, Regional University of Cariri

    Plant Ecology Laboratory, Department of Biology

  • João Tavares Calixto Júnior, Regional University of Cariri

    Systematics Laboratory, Department of Biology

  • Maria Arlene Pessoa da Silva, Regional University of Cariri

    Systematics Laboratory, Department of Biology

  • Irwin Rose Alencar de Menezes, Regional University of Cariri

    Laboratory of Pharmacology and Molecular Chemistry, Department of Chemical Biology

  • José Galberto Martins da Costa, Regional University of Cariri

    Natural Products Research Laboratory, Department of Chemical Biology

  • Marta Maria de Almeida Souza, Regional University of Cariri

    Plant Ecology Laboratory, Department of Biology

References

Abrão F, Costa LDA, Alves JM, Senedese JM, Castro PT, Ambrósio SR, Veneziani RCS, Bastos JK, Tavares DC, Martins CHG (2015) Copaifera langsdorffii oleoresin and its isolated compounds: antibacterial effect and antiproliferative activity in cancer cell lines. BMC Complement Altern Med 15:1-10. https://doi.org/10.1186/s12906-015-0961-4

Albuquerque UP, Alves RRN (2018) Introdução à Etnobiologia. 2 ed. Recife: NUPEEA. 283p.

Albuquerque UP, Lucena RFP, Alencar NL (2010) Métodos e tecnicas para a coleta de dados etnobiolígicos. In: Albuquerque UP, Lucena RFP, Cunha LVFC (ed). Métodos e Técnicas na Pesquisa Etnobiológica e Etnoecológica. Recife: Nupeea. 41-64.

Albuquerque UP, Lucena RFP, Cunha LVFC (2010) Métodos e Técnicas na Pesquisa Etnobiológica e Etnoecológica 1.ed. Recife: NUPEEA. 559p.

Albuquerque UP, Ramos MA, Melo JG (2012) New strategies for drug discovery in tropical forests based on ethnobotanical and chemical ecological studies. J Ethnopharmacol 140:197-201. https://doi.org/10.1016/j.jep.2011.12.042

Alencar ÉN, Xavier-Júnior FH, Morais ARV, Dantas TRF, Dantas-Santos N, Verissimo LM, Rehder VLG, Chaves GM, Oliveira AG, Egito EST (2015) Chemical characterization and antimicrobial activity evaluation of natural oil nanostructured rmulsions. J Nanosci Nanotechnol 15:880-888. https://doi.org/10.1166/jnn.2015.9187

Almeida CFCBR, Amorim ELC, Albuquerque UP (2011) Insights into the search for new drugs from traditional knowledge: An ethnobotanical and chemical–ecological perspective. Pharm Biol 49:864-873. https://doi.org/10.3109/13880209.2010.551777

Almeida SP, Proença CEB, Sano SM, Ribeiro JF (1998) Cerrado: Espécies Vegetais Úteis. 1.ed. Planaltina: EMBRAPA-CPAC. 464p.

Alves JJA, Nascimento SS (2010) Rising fitogeographical of the native medicinal plants of Cariri Paraibano. Rev Geogr Acad 4:73-85.

Amorozo MCM (2002) Uso e diversidade de plantas medicinais em Santo Antônio do Leverger, MT, Brasil. Acta Bot Bras 14:189-203. https://www.scielo.br/pdf/abb/v16n2/a06v16n2

Angiosperm Phylogeny Group – APG IV (2016) An update of the Angiosperm Phylogentic Group classification for the orders and families of flowering plants: APGIV. Bot J Linnean Soc 181:1-20. https://doi.org/10.1111/boj.12385

Araújo MS, Lima MMO (2019) O uso de plantas medicinais para fins terapêuticos: os conhecimentos etnobotânicos de alunos de escolas pública e privada em Floriano, Piauí, Brasil. Amaz RECM 15:235-250. https://doi.org/10.18542/amazrecm.v15i33.5747

Araújo TAS, Alencar NL, Amorim ELC, Albuquerque UP (2008) A new approach to study medicinal plants with tannins and flavonoids contents form the local knowledge. J Ethnopharmacol 120:72-80. https://doi.org/10.1016/j.jep.2008.07.032

Ashraf MU, Muhammad G, Hussain MA, Bukhari SNA (2016) Cydonia oblonga M., a medicinal plant rich in phytonutrients for pharmaceuticals. Frente Farmacol 7:1-20. https://doi.org/10.3389/fphar.2016.00163

Bailey K (1994) Methods of social research. 4 ed. New York: The Free Press. 588p.

Baptistel AC, Coutinho JMCP, Lins Neto EMF, Monteiro JM (2014) Plantas medicinais utilizadas na Comunidade Santo Antônio, Currais, Sul do Piauí: um enfoque etnobotânico. Rev Bras Plantas Med 16:406-425. https://doi.org/10.1590/1983-084X/12_137

Barone JÁ, Coley PD (2002) Herbivorismo y las defensas de las plantas. In: Guariguata MR, Kattan GH (ed). Ecologıa y Conservacion de Bosques Neotropicales. Costa Rica: Libro Universitario Regional, 465-492.

Batista ÂG, Ferrari AS, Cunha DC, Silva JK, Cazarin CBB, Correa LC, Prado MA, Carvalho-Silva LB, Esteves EA, Maróstica Júnior MR (2016) Polyphenols, antioxidants, and antimutagenic effects of Copaifera langsdorffii fruit. Food Chem 197:1153-1159. https://doi.org/10.1016/j.foodchem.2015.11.093

Bitu VCN, Bitu VCN, Matias EFF, Lima WP, Portelo AC, Coutinho HDM, Menezes IRA (2015) Ethnopharmacological study of plants sold for therapeutic purposes in public markets in northeast Brazil. J Ethnopharmacol 172:265-272. https://doi.org/10.1016/j.jep.2015.06.022

Blanckaert I, Vancraeynest K, Swennen RL, Espinosa-García FJ, Piñero D, Lira-Saare R (2007) Non-crop resources and the role of indigenous knowledge in semi-arid production of Mexico. Agric Ecosyst Environ 119:39-48. https://doi.org/10.1016/j.agee.2006.06.015

Brancalion APS, Oliveira RB, Sousa JPB, Groppo M, Berretta AA, Barros ME, Boim MA, Bastos JK (2012) Effect of hydroalcoholic extract from Copaifera langsdorffii leaves on urolithiasis induced in rats. Urol Res 40:475-481. https://doi.org/10.1007/s00240-011-0453-z

Brett JA (1998) Midicinal plant selection criteria: the cultural interpretation of chemicalsenses. Angew Bot 72:70-74.

Brito MFM, Lucena RFP, Cruz DD (2015) Conhecimento etnobotânico local sobre plantas medicinais: uma avaliação de índices quantitativos. Interciência 40:156-164. https://www.redalyc.org/articulo.oa?id=33934728007

Byg A, Balslev H (2001) Diversity and use of palms in Zahamena, easters Madagascar. Biodivers Conserv 10:951-970. https://doi.org/10.1023/A:1016640713643

Carmo JF, Miranda I, Quilhó T, Sousa VB, Cardoso S, Carvalho AM, Carmo FHDJ, Latorraca JVF, Pereira H (2016) Copaifera langsdorffii bark as a source of chemicals: structural and chemical characterization. J Wood Chem Technol 36:305-317. https://doi.org/10.1080/02773813.2016.1140208

Conceição GM, Ruggieri AC, Araujo MFV, Conceição TTMM, Conceição MAMM (2011) Plantas do cerrado: comercialização, uso e indicação terapêutica fornecida pelos raizeiros e vendedores, Sci Plena 7:1-6.

Costa ARM, Freitasa LAP, Mendiola J, Ibáñez, E (2015) Copaifera langsdorffii supercritical fluid extraction: Chemical and functional characterization by LC/MS and in vitro assays. J Supercrit Fluids 100:86-96. https://doi.org/10.1016/j.supflu.2015.02.028

Costa IR, Araújo FS, Lima-Verde LW (2004) Flora e aspectos auto-ecológicos de um encrave de cerrado na chapada do Araripe, Nordeste do Brasil. Acta Bot Bras 18:59-770. https://doi.org/10.1590/S0102-33062004000400006

Costa JAS. Copaifera in Flora do Brasil 2020. Jardim Botânico do Rio de Janeiro. Available at.: http://floradobrasil.jbrj.gov.br/reflora/floradobrasil/FB22896. Accessed on: 13 Jun 2018.

Endara MJ, Coley PD (2011) The resource availability hypothesis revisited: A meta-analysis. Funct Ecol 25:89-398. https://doi.org/10.1111/j.1365-2435.2010.01803.x

Fagundes NCA, Oliveira GL, Souza BG (2017) Etnobotânica de plantas medicinais utilizadas no distrito de Vista Alegre, Claro dos Poções – Minas Gerais. Rev Fitos 11:1-118. https://doi.org/10.5935/2446-4775.20170007

Farias CLA, Martinez GR, Cadena SMSC, Mercê ALR, Petkowicz CLO, Noleto GR (2019) Cytotoxicity of xyloglucan from Copaifera langsdorffii and its complex with oxovanadium (iv/v) on B16F10 cell. Int J Biol Macromol 121:1019-1028. https://doi.org/10.1016/j.ijbiomac.2018.10.131

Ferrão BH, Oliveira HB, Molinari RF, Teixeira MB, Fontes GG, Amaro MOF, Rosa MB, Carvalho CA (2014) Importância do conhecimento tradicional no uso de plantas medicinais em Buritis, MG, Brasil. Ciênc Nat 36:321-334. https://doi.org/10.5902/2179460X13233

Ferreira Júnior WS, Albuquerque UP (2018) A theoretical review on the origin of medicinal practices in humans: echoes from evolution. Ethnobiol Conserv 7:1-7. https://doi.org/10.15451/ec2018–02–7.3–1–7

Flora do Brasil (2018) Flora do Brasil 2020 em construção, Jardim Botânico do Rio de Janeiro. Available at: http://floradobrasil.jbrj.gov.br/. Accessed on: 22 Jan 2019.

Franco SEP, Souza ACR (2016) Resgate do conhecimento sobre as plantas medicinais utilizadas por alunos do programa de ensino de jovens e adultos (EJA) no município de Porto Velho-RO. Rev Saber Científ 5:1-7.

Friedman J, Yaniv Z, Dafni A, Palewith (1986) A preliminary classification of the healing potencial of medicinal plants, based on a rational analysis of an ethnopharmacological field survery among Bedouins in the Negev desert, Israel. J Ethnopharmacol 16:275-287.

Garcia GFC (2006) The mother-child nexus. Knowledge and valuation of wild food plants in Wayanad, Western Ghats, India. J Ethnobiol Ethnomed 39:1-6.

Geck MS, Cabras S, Casu L, Reyes GAJ, Leonti M (2017) The taste of heat: how humoral qualities act as a cultural filter for chemosensory properties guiding herbal medicine. J Ethnopharmacol 198:499-515. https://doi.org/10.1016/j.jep.2017.01.027

Gelmini F, Beretta G, Anselmi C, Centini M, Magni P, Ruscica M, Cavalchini A, Facino RM (2013) GC–MS profiling of the phytochemical constituents of theoleoresin from Copaifera langsdorffii Desf. and a preliminary in vivo evaluationof its antipsoriatic effect. Int J Pharm 440:170-178. https://doi.org/ 10.1016/j.ijpharm.2012.08.021

Gottlieb OR, Borin MRMB (1999) Bioconnectivity: a blueprint for biodiversity? Pure Appl Chem 71:1635-1642. http://www.stats.iupac.org/publications/pac/1999/71_09_pdf/7109gottlieb_1635.pdf

Guarim-Neto G, Morais RG (2003) Recursos medicinais de espécies do Cerrado de Mato Grosso: Um estudo bibliográfico. Acta Bot Bras 17:561-584. https://doi.org/10.1590/S0102-33062003000400009

Herms DA, Mattson WJ (1992) The dilemma of plants: to grow or defend. Q Rev Biol 67:283-335. https://doi.org/doi:10.1086/417659

International Classification Committee- ICPC-2 (2000) International Classification of Primary Care - 2nd Edition. Available at: https://www.who.int/classifications/icd/adaptations/icpc2/en/. Accessed on: 17 Mar 2019.

IPECE. Instituto de Pesquisa e Estratégia Econômica do Ceará (2016) Perfil básico municipal. Available at: http:// www.ipece.ce.gov.br. Accessed on: 14 Mar 2017.

Kong DX, Li XJ, Zhang HY (2009) Where is the hope for drug discovery? Let history tell the future. Drug Discov Today 14:115-119. https://doi.org/10.1016/j.drudis.2008.07.002

Lemos M, Santin JR, Mizuno CS, Boeing T, Sousa JPB, Nanayakkara D, Bastos JK, Andrade SF (2015) Copaifera langsdorffii: evaluation of potential gastroprotective of extract and isolated compounds obtained from leaves. Rev Bras Farmacogn 25:238-245. https://doi.org/ 10.1016/j.bjp.2015.05.005

Lorenzi H (2000) Árvores brasileiras: manual de identificação e cultivo de plantas arbóreas nativas do Brasil. 1 ed. Nova Odessa: Instituto Plantarum. 152p.

Macedo DG, Meneze IRA, Lacerda SR, Silva MAP, Ribeiro DA, Macêdo MS, Oliveira LGS, Saraiva ME, Alencar SR, Oliveira SF, Santos MO, Almeida BV, Macedo JGF, Sousa FFS, Soares MA, Araujo TMS, Souza MMA (2016) Versatility and consensus of the use of medicinal plants in an area of cerrado in the Chapada do Araripe, Barbalha - CE- Brazil. J Med Plant Res 10:505-514. https://doi.org/ 10.5897/JMPR2015.5952

Macêdo DG, Ribeiro DA, Coutinho HDM, Menezes IRA, Souza MMA (2015) Práticas terapêuticas tradicionais: uso e conhecimento de plantas do cerrado no estado de Pernambuco (Nordeste do Brasil). Bol Latinoamer Caribe Plantas Med Aromat 14:491-508. https://www.redalyc.org/articulo.oa?id=85642430007

Macêdo MJF, Ribeiro DA, Santos MO, Macêdo DG, Macedo JGF, Almeida BV, Saraiva ME, Lacerda MNS, Souza MMA (2018) Fabaceae medicinal flora with therapeutic potential in Savanna areas in the Chapada do Araripe, Northeastern Brazil. Rev Bras Farmacogn 28:738-750. https://doi.org/10.1016/j.bjp.2018.06.010

Mariano CRP, Souza EM, Souza KIL, Ferreira LC, Pasa MC (2015) Uso de plantas medicinais pelos acadêmicos da UFMT. Biodiversidade 14:116-124. file:///C:/Users/Maria%20de%20Oliveira/Downloads/2898-8745-1-SM.pdf

Masson-Meyers D, Andrade T, Leite S, Frade M (2013) Cytotoxicity and wound healing properties of Copaifera langsdorffii oleoresin in rabbits. Int J Nat Product Sci 3:10-20.

Mesquita UO, Tavares-Martins ACC (2018) Etnobotánica de plantas medicinales en la comunidad de Caruarú, Isla del Mosqueiro, Belém-PA, Brasil. Bol Latino Caribe Plantas Med Aromat 17:130-159. http://www.revistas.usach.cl/ojs/index.php/blacpma/article/view/3243/2969

MMA. Ministério do Meio Ambiente (2011) Relatório Parametrizado: Unidade de Conservação. Brasília.

Moreira DL, Guarim-Neto G (2009) Usos múltiplos de plantas do cerrado: um estudo etnobotânico na comunidade sítio Pindura, Rosário Oeste, Mato Grosso, Brasil. Polibotánica 27:159-190. https://www.researchgate.net/publication/237217702

Mori LA, Silva LAM, Lisboa G, Coradin L (1989) Manual de manejo do herbário fanerogâmico. 2 ed. Ilheus: Centro de Pesquisa de Cacau -CEPLAC. 104p.

Motta EVS, Lemos M, Costa JC, Banderó-Filho VC, Sasse A, Sheridan H, Bastos JK (2017) Galloylquinic acid derivatives from Copaifera langsdorffii leaves display gastroprotective activity. Chem-Biol Interact 261:145-155. https://doi.org/10.1016/j.cbi.2016.11.028

Nascimento FG, Faqueti A, Wilhelm JF, Wittkowski C, Tomczak FD, Borges SL, Yunes RA, Franchi Jr GC, Nowill AE, Cechinel Filho V, Machado MS, Freitas RA, Malheiros  (2014) Seasonal influence and cytotoxicity of extracts, fractions and major compounds from Allamanda schottii. Rev Bras Farmacogn 24:545-552. https://doi.org/10.1016/j.bjp.2014.08.005

Oliveira DR, Ferreira Júnior WS, Bitu VCN, Pinheiro PG, Menezes CDA, Brito Junior FE, Albuquerque UP, Kerntopf MR, Coutinho HDM, Fachinetto R, Menezes IRA (2014) Ethnopharmacological study of Stryphnodendron rotundifolium in two communities in the semi-arid region of northeastern Brazil. Rev Bras Farmacogn 24:124-132. https://doi.org/10.1016/j.bjp.2014.03.003

Oliveira FCS, Barros RFM, Moita Neto JM (2010) Plantas medicinais utilizadas em comunidades rurais de Oeiras, semiárido piauiense. Rev Bras Plantas Med 12:282-301. https://doi.org/ 10.1590/S1516-05722010000300006

Oliveira-Silva KL, Ramos YJ, Oliveira GC, Fonseca IC, Gonçalves JA, Souza UC, Defaveri ACA, Silva JC, Almeida MZ, Pantoja SCS (2018) Estratégia de ensino e avaliação do curso de extensão em Cultivo de Plantas Medicinais do Jardim Botânico do Rio de Janeiro. RBCS 30:168-181. https://doi.org/ 10.14295/vittalle.v30i1.7484

Paiva LAF, Alencar CKM, Santos FA, Gramosa NV, Silveira ER, Rao SN (2002) Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffi in rats. Phytother Res 16:737-739. https://doi.org/10.1002/ptr.1049

Paiva LAF, Gurgel LA, Silva RM, Tomé AR, Gramosa NV, Silveira ER, Santos FA, Rao VSN (2003) Anti-inflammatory effect of kaurenoic acid, a diterpene from Copaifera langsdorffii on acetic acid induced colitis in rats. Vasc Pharmacol 39:303-307. https://doi.org/10.1016/S1537-1891(03)00028-4

Paiva LAF, Gurgel LA, Sousa ET, Silveira ER, Silva RM, Santos FA, Rao VSN (2004) Protective effect of Copaifera langsdorffii oleo-resin against acetic acid-induced colitis in rats. J Ethnopharmacol 93:51-6. https://doi.org/10.1016/j.jep.2004.03.028

Palmer C (2004) Plantago spp. and Bidens sp.: A case study of change in Hawaiian herbal medicine. J Ethnobiol 24:13-31.

Penido AB, Morais SM, Ribeiro AB, Silva AZ (2016) Ethnobotanical study of medicinal plants in Imperatriz, State of Maranhão, Northeastern Brazil. Acta Amazon 46:345-354. https://doi.org/10.1590/1809-4392201600584

Pereira NV, Magalhaes TR, Macedo T, Pasa MC (2016) Recursos vegetais e o saber local: uso de plantas medicinais no horto florestal Toti Garcia, Cuiabá MT. Biodiversidade 15:124-135. http://periodicoscientificos.ufmt.br/ojs/index.php/biodiversidade/article/view/3965/2760

Phillips O, Gentry AH (1993) The useful plants of Tambopata, Peru: I. Statistical hypotheses tests with a new quantitative technique. Econ Bot 47:15-32. https://doi.org/10.1007/BF02862203

Pieri FA, Souza CF, Costa JCM, Barrero MAO, Espeschit IF, Silva VO, Moreira MAS (2011) Inibição de Escherichia coli de leite mastítico pelo óleo de copaíba. Semin Cienc Agrar 32:1929-1934. https://doi.org/10.5433/1679-0359.2011v32n4Sup1p1929

Pinto SME, Tresvenzol LMF, John RRL, Alves EO, Paula JR, Fiuza TS (2013) Uso popular de plantas medicinais pelas comunidades de Três Lagoas/MS, Porto Velho/RO e Rio Verde/GO. Infarma: Ciênc Farmac 25:76-87.

Ribeiro DA, Damasceno SS, Boligon AA, Menezes IRA, Souza MMA, Costa JGM (2017) Chemical profile and antimicrobial activity of Secondatia floribunda A. DC. (Apocynaceae). Asian Pac J Trop Biomed 7:739-749. https://doi.org/ 10.1016/j.apjtb.2017.07.009

Ribeiro DA, Oliveira LGS, Macêdo DG, Menezes IRA, Costa JGM, Silva MAP, Lacerda SR, Souza MMA (2014) Promising medicinal plants for bioprospection in a Cerrado area of Chapa do Araripe, Northe rastern Brazil. J Ethnopharmacol 155:1522-1533. https://doi.org/10.1016/j.jep.2014.07.042

Ronchi HS, Bonfim FPG, Coutinho ET, Martins LA, Engel VL (2016) Potencial medicinal de espécies arbóreas de um remanescente florestal da floresta estacional semidecidual, na região central do estado São Paulo. Encicl Biosf 13:986-1001. https://doi.org/10.18677/Enciclopedia_Biosfera_2016_085

Santos JEG, Bezerra José WA, Silva VB, Linhares KV, Oliveira AA, Campos NB, Bezerra JS, Silva DL, Monte JS, Mendonça ACAM, Souza MMA, Silva MAP (2019) Phytosociology a humid forest of the Chapada of Araripe, Crato, CE, Brazil. J Agric Sci 11:115-129. https://doi.org/10.5539/jas.v11n7p115

Santos MO, Camilo CJ, Ribeiro DA, Macedo JGF, Nonato CFA, Rodrigues FFG, Costa JGM, Souza MMA (2022a) Chemical composition variation of essential oils of Copaifera langsdorffii Desf. from different vegetational formations. Nat Prod Res https://doi.org/10.1080/14786419.2022.2081849

Santos MO, Almeida BV, Campos NB, Macedo JGF, Macêdo MJF, Ribeiro DA, Silva MAP, Calixto Júnior JT, Costa JGM, Souza MMA (2022b) Vegetative and reproductive phenology of Copaifera langsdorffii Desf. in different phytophysiognomies. Res Soc Dev https://doi.org/10.33448/rsd-v11i4.27288

Santos MO, Camilo CJ, Macedo JGF, Lacerda MNS, Lopes CMU, Rodrigues AYF, Costa JGM, Souza MMA (2022c) Copaifera langsdorffii Desf.: A chemical and pharmacological review. Biocatal Agric Biotechnol https://doi.org/10.1016/j.bcab.2021.102262

Santos MRA, Lima MR, Oliveira CLLG (2014) Medicinal plants used in Rondônia, Western Amazon, Brazil. Rev Bras Plantas Med 16:707-720. https://doi.org/10.1590/1983-084x/13_102

Santos MV, Vieira IR, Silva MFS, Andrade IM (2019) Comercialização de plantas medicinais nos mercados públicos do Município de Parnaíba, Piauí, Brasil. Rev Espac 40:1-10. http://www.revistaespacios.com/a19v40n22/a19v40n22p01.pdf

Santos RLG, Guimaraes GP, Nobre MSC, Portela AS (2011) Analysis about phytotherapy as an integrating practice in the Brazilian Unified Health System (UHS). Rev Bras Plantas Med 13:486-491. https://doi.org/10.1590/S1516-05722011000400014

Saraiva ME, Ulisses AVRA, Ribeiro DA, Oliveira LGS, Macêdo DG, Sousa FDFS, Menezes IRA, Sampaio EVSB, Souza MMA (2015) Plant species as a therapeutic resource in áreas of the savann in the state of Pernambuco, Northeast Brazil. J Ethnopharmacol 171:141-153. https://doi.org/10.1016/j.jep.2015.05.034

Schiavo M, Schwambach KH, Colet CF (2017) Conhecimento sobre plantas medicinais e fitoterápicos de agentes comunitários de saúde de Ijuí/RS. J Fund Care Online 9:57-63. https://doi.org/10.9789/2175-5361.2017.v9i1.57-63

Senedese JM, Alves JM, Lima IMS, Andrade EAP, Furtado RA, Bastos JK, Tavares DC (2013) Chemopreventive effect of Copaifera langsdorffii leaves hydroalcoholic extract on 1,2-dimethylhydrazine-induced DNA damage and preneoplastic lesions in rat colon. BMC Complement Altern Med 13:1-8. https://doi.org/10.1186/1472-6882-13-3

Shepard GH (2004) A sensory ecology of medicinal plant therapy in two Amazonian societies. Am Anthropol 106:252-266.

Silva JDA, Nascimento MGP, Grazina LG, Castro KNC, Mayo SJ, Andrade IM (2015) Ethnobotanical survey of medicinal plants used by the community of Sobradinho, Luís Correia, Piauí, Brazil. J Med Plant Res 9:872-883. https://doi.org/10.5897/JMPR2015.5881

Silva JJL, Guimarães SB, Silveira ER, Vasconcelos PRL, Lima GG, Torres SM, Vasconcelos RC (2009) Effects of Copaifera langsdorffii Desf. on ischemia-reperfusion of randomized skin flaps in rats. Aesthetic Plast Surg 33:104-109. https://doi.org/10.1007/s00266-008-9263-2

Silva RC, Roriz BC, Santos CS (2018) Etnoconhecimento sobre as espécies medicinais utilizadas pela população de Araguaína, TO. Rev São Luís Orion 1:1-21.

Silva WAG, Linhares KV (2011) Plano de ação nacional para a conservação do soldadinho-do-araripe 15, séries ameaçadas Brasília. Available at: http://www.icmbio.gov.br/portal/images/stories/docs-plano-de-acao/pansoldadinhoararipe/web-pan-soldadinho-do-araripe.pdf. Accessed on: 03 November 2018)

Sousa JPB, Brancalion APS, Souza AB, Turatti ICC, Ambrósio SR, Furtado NAJC, Lopes NP, Bastos JK (2011) Validation of a gas chromatographic method to quantify sesquiterpenes in copaiba oils. J Pharm Biomed Anal 54:653-659. https://doi.org/10.1016/j.jpba.2010.10.006

Souza CD, Felfili JM (2006) Uso de plantas medicinais na região de Alto Paraíso de Goiás. Acta Bot Bras 20:135-142. https://doi.org/10.1590/S0102-33062006000100013

Souza MJN, Oliveira VPV (2006) Os enclaves úmidos e sub-úmidos do semi-árido do Nordeste Brasileiro. Mercator 5:85-102. http://www.repositorio.ufc.br/handle/riufc/2106

Souza RKD, Silva MAP, Menezes IRA, Ribeiro DA, Bezerra LR, Souza MMA (2014) Ethnopharmacology of medicinal plants of Carrasco, northeastern of Brazil. J Ethnopharmacol 157:99-104. https://doi.org/10.1016/j.jep.2014.09.001

Stepp JR, Moerman DE (2001) The importance of weeds in ethnopharmacology. J Ethnopharmacol 75:19-23. https://doi.org/10.1016/S0378-8741(00)00385-8

Vargas FDS, Almeida PDO, Aranha ESP, Boleti APDA, Newton P, Vasconcellos MC, Veiga VF, Lima ES (2015) Biological activities and cytotoxicity of diterpenes from Copaifera spp. Oleoresins. Molecules 20:6194-6210. https://doi.org/10.3390/molecules20046194

Verma N, Shukla S (2015) Impact of various factors responsible for fluctuation inplant secondary metabolites. J Appl Res Med Aromat Plants 2:105-113. https://doi.org/10.1016/j.jarmap.2015.09.002

Downloads

Published

2023-08-15

Issue

Vol. 25 No. 2 (2023)

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

Consensus of the medicinal use of Copaifera langsdorffii Desf. in different phytophysiognomies. (2023). Revista Brasileira De Plantas Medicinais Brazilian Journal of Medicinal Plants, 25(2), 73-94. https://doi.org/10.70151/2hz8n979